Evodiamine is a bioactive alkaloid extract from a plant called Evodiae Fructus. This is a Chinese herb named Wu-Chu-Yu that Chinese herbalists have used for centuries as a weight loss supplement. Evodiamine is related to capsaicin or the spicy flavor of peppers. It acts as a vanilloid receptor agonist, and can enhance lipolytic (breakdown of fat) activity, enhance insulin secretion and sensitivity.
Interestingly enough, Evodiamine can raise the body’s skin temperature while simultaneously decreasing core temperature, similar to a hypothermic state. Studies have shown that this is an effective process to burn calories and fat for energy while the body increases its temperature.
